What We Study

Activity- and drug-induced alterations in synaptic plasticity can lead to long-lasting changes at synapses that remodel neuronal circuits and regulate processes like learning and memory, neurodegeneration, and drug addiction. Our lab is broadly interested in the cell biology of neurons and synaptic junctions. More specifically, we are characterizing molecular processes that underlie the assembly and proper synaptic delivery and retention of proteins important for synaptic transmission and plasticity. These studies make use of rodent cellular models, recombinant DNA technology, biochemical assays and, most prominently, fluorescent light microscopic techniques. Please explore the “projects” section to read more about specific projects.